Barberry may help with an enlarged spleen. One constituent, berberine, may have antibiotic properties. According to Michael Castleman in The Healing Herbs, barberry may also stimulate the immune system and may activate macrophages. Other sources state that it helps bile flow.

Boldo is an evergreen shrub that grows in the Andes Mountains. It is said to help with gallbladder problems. One constituent, ascaridole, is said to function as a vermifuge, which expels intestinal worms.

Buckthorn is a depurative, which promotes the excretion and removal of waste material. It is also a mild laxative, due to its anthraquinone content, and is said to aid bile production.

Burdock root has a long history as a detoxifier. In Herbal Medications, A.W. and L.R. Priest note that burdock can be used “… to remove accumulated waste products.” It is also known to help with lymphatic congestion.

Cascara sagrada, like buckthorn root, contains anthraquinone and is thus a mild laxative. It is also a general tonic that promotes well-being in all body systems.

Chickweed boasts many folk remedies, and is said to be good for the blood and joints.

Dandelion has a distinguished history as a detoxifier. Joseph Pizzorno and Michael Murray, in A Textbook of Natural Medicine, call it a fine remedy for a toxic liver. The Ayurvedic physician Vasant Lad and David Frawley, in The Yoga of Herbs, say dandelion is also good for the lymph glands, and Santillo, in Natural Healing with Herbs, classifies it as a lymphatic, which cleanses the lymphatic system.

Echinacea was used by Native Americans, and today, it is recognized as an aid to the immune system. Echinacea contains echinacoside, a natural antibiotic, which is probably responsible for antibiotic properties. Studies in Europe have shown that echinacea increases production of T cells. Santillo classifies it as a lymphatic, which cleanses the lymphatic system.

Licorice is well-known as a powerful herb. According to a report in Microbiology and Immunology, licorice may stimulate cell production of interferon. Asian studies and studies published in the Plant Medica (1984: 50) have shown it to be helpful for the liver.

From the 1850s to 1926, parsley was recognized by the United States Pharmacopoeia as a laxative and a diuretic. Today, it is more commonly used as a breath freshener.

Sarsaparilla, according to Pizzorno and Murray in A Textbook of Natural Medicine, has been used in Europe since the sixteenth century as a blood purifier. Sarsaparilla is also said to bind to endotoxins and escort them out of the body. If endotoxins remain in the body they can contribute to a number of health-related problems.